TABLE 3.
Comparison of the degrees of lymphocyte depletion of different lymphoid tissues with respect to the apparent amount of PCV2 DNA genome observed after ISH
Level of PCV2 DNA (no. of pigsb) | No. of PCV2-positive pigs showing indicated degree of lymphocyte depletion in indicated tissuea
|
|||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Superficial inguinal LNc
|
Mesenteric LN
|
Peyer's patches
|
Tonsil
|
Spleen (PALSd)
|
||||||||||||||
B zonee
|
T zonef
|
B zone
|
T zone
|
B zone
|
T zone
|
B zoneg
|
T zoneh
|
|||||||||||
1 | 2 or 3 | 1 | 2 or 3 | 1 | 2 or 3 | 1 | 2 or 3 | 1 | 2 or 3 | 1 | 2 or 3 | 1 | 2 or 3 | 1 | 2 or 3 | 1 | 2 or 3 | |
Low (7) | 4 | 0 | 0 | 0 | 3 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 3 | 0 | 1 | 0 | 1 | 0 |
High (17) | 0 | 15 | 8 | 9 | 0 | 17 | 1 | 16 | 0 | 16 | 1 | 16 | 1 | 13 | 4 | 9 | 5 | 7 |
Score of lymphocyte depletion degree: 1, slight; 2, moderate; 3, severe.
Total number of pigs, including those not showing lymphocyte depletion.
LN, lymph node.
PALS, periarteriolar lymphoid sheaths; P = 0.07.
B zone, B-cell-dependent area.
T zone, T-cell-dependent area.
P < 0.01; for other groups, P < 0.001, except as indicated.
P < 0.05.