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. 2005 Sep 2;33(15):4914–4921. doi: 10.1093/nar/gki799

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© The Author 2005. Published by Oxford University Press. All rights reserved

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Global gene expression profiles during zebrafish embryogenesis. All transcripts with >10-fold change in expression from 1.5–24 h post-fertilization (hpf) identified by zebrafish-specific microarray analysis are clustered according to similar time-dependent expression patterns with upregulated expression in red, downregulated genes in green and unchanged expression in black. Panel 1 shows those steady-state mRNAs that are markedly downregulated when embryonal transcription commences, including ccnb1, ccnb2 and ccne (highlighted). Panels 2 and 3 present those transcripts that are markedly upregulated after MBT at 6 and 24 hpf, respectively.