Table 3.
Odds ratios (or) of thyroid hormone sensitivity indices to histological characteristics in DTC patients.
| Thyroid hormone sensitivity indices |
||||
|---|---|---|---|---|
| FT3/FT4 | TFQI | |||
| Outcome variables | OR (95% CI) | p value | OR (95% CI) | p value |
| Angioinvasion | 1.49 (1.14, 1.94) | .003 | 0.67 (0.47, 0.96) | .028 |
| Nerve invasion | 0.81 (0.47, 1.40) | .456 | 1.04 (0.60, 1.79) | .901 |
| Margin involvement | 1.05 (0.94, 1.16) | .401 | 1.09 (0.98, 1.22) | .106 |
| Lymph node metastases | 1.16 (1.04, 1.29) | .008 | 0.84 (0.75, 0.94) | .002 |
| Multifocal | 1.02 (0.92, 1.14) | .681 | 0.95 (0.85, 1.06) | .385 |
| Bilobar | 0.95 (0.85, 1.08) | .446 | 0.98 (0.87, 1.11) | .727 |
| Extrathyroidal invasion | 1.01 (0.87, 1.17) | .925 | 1.03 (0.88, 1.20) | .757 |
| Invasive pathological variants | 1.38 (1.01, 1.89) | .042 | 0.75 (0.39, 1.46) | .401 |
| Tumor size | 0.35 (−0.06, 0.76) | .094 | 0.26 (−0.13, 0.65) | .195 |
The evaluation of the OR and 95% confidence interval (CI) was conducted using multivariable logistic regression models.
Adjusted model: adjusted for sex, age, BMI, TgAb-positive, TPOAb-positive, hashimoto thyroiditis.
DTC: differentiated thyroid cancer; FT3: free triiodothyronine; FT4: free thyroxine; TFQI: thyroid feedback quantile-based index; BMI: body mass index; TgAb: thyroglobulin antibody; TPOAb: thyroid peroxidase antibody.