Table 3.
Factors associated with parental concerns, specialist referral, impact of behaviour on the family, and parental anxiety, at 3 years, adjusted for centre and congenital infection status(Total N = 705)
| Odds ratio for outcome (95% confidence interval) | ||||
| EXPOSURES | Any concerns5 | Any referral | Behaviour impact4 | Parental anxiety3 |
| Before birth | ||||
| 1) Congenital toxoplasmosis (reference = uninfected) | 0.98 (0.95, 1.01) | 2.00 (0.90, 4.45) | 0.55 (0.22, 1.39) | 3.01 (1.84, 4.94) |
| 2) Maternal Age1 | 0.97 (0.92, 1.03) | 0.96 (0.89, 1.05) | 0.98 (0.90, 1.07) | 0.98 (0.93, 1.03) |
| 3) Parity1 | 0.96 (0.81, 1.15) | 1.05 (0.72, 1.54) | 0.98 (0.66, 1.44) | 1.26 (1.06, 1.50) |
| 4) Maternal Education1 | 0.91 (0.73, 1.14) | 0.77 (0.51, 1.16) | 1.18 (0.81, 1.74) | 0.82 (0.65, 1.04) |
| 5) Mother born outside country2 (no = reference) | 1.59 (0.84, 3.01) | 0.82 (0.18, 3.79) | 2.20 (0.86, 5.60) | 1.06 (0.51, 2.21) |
| 6) Child's gender (male = reference) | 1.89 (1.22, 2.93) | 0.83 (0.39, 1.73) | 0.99 (0.50, 1.96) | 1.26 (0.81, 1.94) |
| 7) Duration of prenatal treatment (wks) | 0.98 (0.96, 1.00) | 1.00 (0.96, 1.04) | 1.01 (0.97, 1.05) | 0.97 (0.94, 0.99) |
| After birth | ||||
| 8) Child's age at Questionnaire1 (month) | 0.97 (0.90, 1.04) | 1.07 (0.97, 1.19) | 1.02 (0.93, 1.13) | 0.97 (0.90, 1.04) |
1Odds ratio expresses risk of adverse developmental/behavioural outcome per unit increase in exposure, adjusted for centre and congenital infection status
2Odds ratio expresses risk of adverse developmental/behavioural outcome, adjusted for centre and congenital infection status
3Adverse outcome defined by score corresponding most closely to the least able/most worried 10% in the uninfected children
4Adverse outcome defined by developers of SDQ questionnaire.
5Defined by answering 'yes' or 'a little' to question(s) about concerns.