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. Author manuscript; available in PMC: 2026 Apr 1.
Published in final edited form as: Neurogastroenterol Motil. 2024 Dec 31;37(4):e14992. doi: 10.1111/nmo.14992

Table 7.

Associations of demographic and other social factors with anxiety and depression

Measure PROMIS anxiety PROMIS depression
No
(n = 68)
Yes
(n = 52)
OR (95%CI) P
value
No
(n = 77)
Yes
(n = 16)
OR (95%CI) P
value
Age groups
Older (13 – 18 years) 55.0 33.0 1.0 (1.0–6.1) 0.03 55.0 10.0 1.0 (0.4–5.2) 0.48
Younger (10 – 12 years) 13.0 19.0 2.4 (1.0–6.1) 22.0 6.0 1.5 (0.4–5.2)
Gender
Male 27.0 33.0 1.0 (0.2–0.9) 0.01 43.0 13.0 1.0 (0.04–1.2) 0.06
Female 41.0 19.0 0.4 (0.2–0.9) 34.0 3.0 0.3 (0.04–1.2)
Race
Black
No 64.0 46.0 1.0 (0.5–10.6) 0.27 73.0 12.0 1.0 (1.0–36.5) 0.01
Yes 4.0 6.0 2.1 (0.5–10.6) 4.0 4.0 6.1 (1.0–36.5)
White
No 44.0 37.0 1.0 (0.3–1.7) 0.45 51.0 12.0 1.0 (0.1–2.5) 0.49
Yes 24.0 15.0 0.7 (0.3–1.7) 26.0 4.0 0.7 (0.1–2.5)
Mixed
No 31.0 24.0 1.0 (0.4–2.2) 0.95 33.0 10.0 1.0 (0.1–1.5) 0.15
Yes 37.0 28.0 1.0 (0.4-2.2) 44.0 6.0 0.5 (0.1-1.5)
Native
No 65.0 49.0 1.0 (0.2–10.3) 0.74 74.0 14.0 1.0 (0.3–33.2) 0.17
Yes 3.0 3.0 1.3 (0.2–10.3) 3.0 2.0 3.5 (0.3–33.2)
Birth history
Delivery via cesarean section
No 50.0 36.0 1.0 (0.5–3.0) 0.60 55.0 11.0 1.0 (0.3–4.1) 0.83
Yes 18.0 16.0 1.2 (0.5–3.0) 22.0 5.0 1.1 (0.3–4.1)
Premature birth
No 49.0 31.0 1.0 (0.4–4.6) 0.53 53.0 10.0 1.0 (0.3–12.1) 0.28
Yes 9.0 8.0 1.4 (0.4–4.6) 7.0 3.0 2.3 (0.3–12.1)
Sibling status
Only child
No 58.0 47.0 1.0 (0.2–2.2) 0.40 68.0 13.0 1.0 (0.3–8.3) 0.44
Yes 10.0 5.0 0.6 (0.2–2.2) 9.0 3.0 1.7 (0.3–8.3)
First-born child
No 37.0 30.0 1.0 (0.4–1.9) 0.72 42.0 11.0 1.0 (0.1–1.9) 0.30
Yes 31.0 22.0 0.9 (0.4–1.9) 35.0 5.0 0.5 (0.1–1.9)
Parental marital status
Parents divorced or separated
No 30.0 25.0 1.0 (0.4–1.9) 0.67 35.0 7.0 1.0 (0.3–3.8) 0.90
Yes 38.0 27.0 0.9 (0.4–1.9) 42.0 9.0 1.1 (0.3–3.8)
Family and past history
Family history of DGBIs
No 39.0 30.0 1.0 (0.01–3.6) 0.30 44.0 10.0 n/a
Yes 4.0 1.0 0.3 (0.01–3.6) 4.0 0.0
Previous history of dengue
No 64.0 51.0 1.0 (0.01–3.3) 0.28 74.0 15.0 1.0 (0.02–22.0) 0.67
Yes 4.0 1.0 0.3 (0.01–3.3) 3.0 1.0 1.6 (0.02–22.0)

Data is formatted as value. PROMIS: Patient Reported Outcomes Measurement Information System, OR: Odds ratio, CI: Confidence Interval, DGBIs: Disorders of Gut-Brain Interaction.