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. 2025 Apr 1;16:1529528. doi: 10.3389/fphar.2025.1529528

TABLE 3.

Association of Gliflozin use with demographic and clinical factors.

Variable Category Gliflozin use (No) N (%) Gliflozin use (Yes) N (%) Total N (%) P-value
Gender Female 53 (72.6) 20 (27.4) 73 (100) 0.203
Male 117 (64.3) 65 (35.7) 182 (100)
Age groups (years) 27–40 13 (76.5) 4 (23.5) 17 (100) 0.089
41–55 52 (67.5) 25 (32.5) 77 (100)
56–70 55 (57.9) 40 (42.1) 95 (100)
>70 50 (75.8) 16 (24.2) 66 (100)
BMI groups 18.5–24.99 (Normal) 50 (83.3) 10 (16.7) 60 (100) 0.002 a
25–29.9 - ≥30 (Overweight - Obese) 120 (61.5) 75 (38.5) 195 (100)
HbA1c Group Less than <5.7 (normal) 26 (78.8) 7 (21.2) 33 (100) <0.001 a
5.7–6.4 (Prediabetes) 38 (79.1) 10 (20.9) 48 (100)
≥6.5 (Diabetes) 47 (49.0) 49 (51.0) 96 (100)
Diagnosed with diabetes Yes 110 (60.1) 73 (39.9) 183 (100) <0.001 a
No 58 (85.3) 10 (14.7) 68 (100)
Comorbidity/complications HF 25 (38.5) 40 (61.5) 65 (100) <0.001 a
CKD 145 (76.3) 45 (23.7) 190 (100)
CKD with diabetes 97 (70.8) 40 (29.2) 137 (100) <0.001 a
CKD with no diabetes 46 (92.0) 4 (8.0) 50 (100)
HF with diabetes 13 (28.3) 33 (71.7) 46 (100)
HF with no diabetes 12 (66.7) 6 (33.3) 18 (100)
a

Significant value. HF, Heart Failure; CKD, chronic kidney disease.