Table 2.
α-syn PFF-induced deficits, L-DOPA reversibility, and correlation with striatal DA summary.
| Behavior | α-syn PFF-induced deficit | L-DOPA reversible | Striatal DA correlation |
|---|---|---|---|
| Movement initiation | |||
| Mean of 3 trials | Yes | Yes | Yes |
| Somatosensory asymmetry | |||
| Contact | Yes | No | Yes |
| Spontaneous activity | |||
| Hindlimb steps | Yes | Yes | No |
| Object recognition | |||
| Rears | Yes | NA | Yes |
| Investigation time | Yes | NA | Yes |
NA, not assessed.