FIG. 1.

Low-dose UVB irradiation suppresses the lesion development of cutaneous L. amazonensis infection. BALB/c mice were irradiated with UVB at 250 J/m² for 4 consecutive days; 12 h later, control and irradiated mice were injected with 2 × 10⁶ L. amazonensis promastigotes. Three weeks after inoculation, visible skin lesions were measured weekly, and size was calculated by measuring length and width. Nonirradiated and irradiated mice were killed at 12 weeks after inoculation. Data presented here are the means and standard deviations from a representative experiment repeated three times with the same results. Statistically, the significance of the difference between the groups was analyzed by Student's unpaired t test. An asterisk indicates a P value of <0.0008.