Table 3:
Number of adverse events and the IRR for events in group APD versus events in group RM-APD, adjusting for patients’ identification and centers.
| Type of event | Crude APD/RM-APD | IRR (95% CI) | P > |z| |
|---|---|---|---|
| PD infection events | 100/86 (P = .12) | 1.28 (0.69–2.37) | .42 |
| Mechanical events | 33/62 (P = .001) | 0.42 (0.18–0.98) | .04 |
| Intra-abdominal pressure events | 6/13 (P = .07) | 0.48 (0.16–1.40) | .18 |
| Fluid balance events | 123/35 (P = .001) | 3.44 (1.95–6.07) | .001 |
| Cardiovascular events | 79/44 (P = .02) | 1.81 (1.03–3.09) | .03 |
| Metabolic events | 108/44 (P = .001) | 2.78 (1.51–5.38) | .005 |
| Other events | 53/77 (P = .005) | 1.01 (0.45–2.29) | .97 |
| Mechanical hospitalization events | 18/45 (P = .004) | 0.41 (0.22–0.66) | .001 |
| FOL and IDE hospitalizations | 19/7 (P = .01) | 3.24 (1.24–7.53) | .03 |
| All-cause deaths | 55/33 (P = .01) | 1.82 (1.18–2.81) | .006 |
| Cardiovascular deaths | 24/13 (P = .05) | 2.03 (1.03–3.97) | .04 |
Data are expressed as mean ± standard deviation.
Bold font indicates significant difference between APD and RM-APD.
Crude APD/RM-APD = crude analysis of number of adverse events with APD vs RM-APD is calculated with Chi-square test. IRR is calculated with zero-inflated Poisson regression model with Bayesian method. IRR adjusts for patients’ identification and centers.
PD infection events: sum of exit site infection + tunnel infection + peritonitis.
Mechanical events: sum of kinking + disconnection + catheter removal + sleeve extrusion (bearing extortion).
Intra-abdominal pressure events: sum of abdominal discomfort + peritoneal/pleural fistula + intra-abdominal pressure + leakage + hemoperitoneum + hernia.
Fluid balance events: sum of pleural effusion + dehydration + overhydration.
Cardiovascular events: sum of unstable angina + hypertensive crisis + stroke + heart failure + hypotension + acute myocardial infarct + congestive heart failure + chronic heart failure + convulsion + syncope + sudden death.
Metabolic events: sum of malnutrition + hyperglycemia + hypoglycemia + hyperkalemia + hyponatremia + diabetic foot + acid base disorder + uremia.
Other events: sum of gastrointestinal disorders + urinary tract infection + respiratory tract infection.
FOL and IDE hospitalizations: hospitalizations due to fluid overload (FOL) and insufficient dialysis efficiency (IDE).