FIG. 2.

Reduction of TT-induced IL-2 production from T cells by GtfC-GtfD. T cells from one donor were cultured with irradiated autologous PBMC in the presence of TT added at different concentrations as indicated. IL-2 production stimulated by TT alone (black bars) was inhibited by either GtfD (hatched bars) or GtfC (light gray bars) at a concentration of 10 μg/ml. Each bar represents the mean + standard deviation from triplicate assays. The percent inhibition by the addition of either GtfC or GtfD was statistically significant at each concentration of TT with the two-sample t test (P < 0.01).