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. 2025 Mar 17;17(3):e80733. doi: 10.7759/cureus.80733

Figure 3. LC/MS analysis of the nicotine concentrations in the samples of HTPE and CSE.

Figure 3

(A) Chromatogram of HTPE in PBS.

(B) Chromatogram of CSE in PBS.

Analyses performed by Shimadzu Techno-Research, Inc., Kyoto, Japan.

LC/MC: liquid chromatography-mass spectrometry; HTPE: heated tobacco product extract; CSE: cigarette smoke extract; PBS: phosphate-buffered saline