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. 2025 Apr 3;16:1541809. doi: 10.3389/fendo.2025.1541809

Table 1.

Metalloprotein species of essential metals and their functions.

Essential metals Metalloproteins Function
Fe Hemoglobin Oxygen carrying and storage
Myoglobin Oxygen carrying and storage
Cytochrome C Electron transporter
Cu Cu, Zn superoxide dismutase (SOD1) Superoxide detoxification, signaling
Lysyl oxidase (LOX) Crosslinking of collagen and elastin
Ceruloplasmin (Cp) Ferroxidase
Cytochrome c oxidase Oxidative phosphorylation
Zn Carbonic anhydrase Catalyze the hydration of carbon dioxide
Zinc finger protein Bind nucleic acids (DNA or RNA)
Ca Calcium-binding protein Control cytoplasmic Ca2+ concentration. Function as Ca2+ transporters and calcium-sensors with regulatory potential