Table 3.
Association between MMR and microscopic traits
| Microscopic feature | dMMR | pMMR | |||
| n | % | n | % | p | |
| Lauren | |||||
| Intestinal | 26 | 17.8 | 120 | 82.2 | 0.010 |
| Diffuse | 1 | 2.9 | 33 | 97.1 | |
| Unidentified | 2 | 4.3 | 44 | 95.7 | |
| WHO | |||||
| Tubular, papillary | 21 | 16.8 | 104 | 83.2 | 0.034 |
| Mucinous | 5 | 19.2 | 21 | 80.8 | |
| SRC | 1 | 4.8 | 20 | 95.2 | |
| Poorly differentiated, poorly adhesive, specifics | 2 | 3.0 | 65 | 97.0 | |
| MSM | |||||
| MSM/non-diffuse | 4 | 18.2 | 18 | 81.8 | p1 = 0.244 p2 = 0.573 p3 = 0.165 |
| MSM/diffuse | 1 | 3.8 | 25 | 96.2 | |
| Non-MSM/non-diffuse | 24 | 14.4 | 143 | 85.6 | |
| Non-MSM/diffuse | 0 | 0 | 11 | 100 | |
| Differentiated grade | |||||
| Differentiated | 22 | 18.5 | 97 | 81.5 | 0.007 |
| Undifferentiated | 7 | 6.5 | 100 | 93.5 | |
| MLC | |||||
| Non-diffuse/proximal | 3 | 25.0 | 9 | 75.0 | 0.056 |
| Non-diffuse/distal | 25 | 14.4 | 149 | 85.6 | |
| Diffuse | 1 | 2.5 | 39 | 97.5 | |
MMR: mismatch repair
dMMR: deficient mismatch repair
pMMR: proficient mismatch repair
SRC: signet ring cell
WHO: World Health Organization
MSM: mucinous-secreting morphology
MLC: Tumor Location-Modified Lauren classification
p1 Comparison between 4 categories in mucinous secreting morphology
p2 Comparison between MSM and non-MSM
p3 Comparison between MSM/intestinal and MSM/diffuse