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Antigenicity of recombinant L. braziliensis histone H1. The reactivities of 24 serum samples from patients with CL, 10 serum samples from patients with ChD, and 12 control serum samples (8 from Peruvian patients and 4 from Spanish patients) were assayed by ELISA. The cutoff line was established as the mean reactivity value plus 3 SDs for the control sera.
