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. 2005 Sep 2;1(3):e30. doi: 10.1371/journal.pgen.0010030

Figure 3. Telomere Length Is Independent from Organismal Life Span and Thermo Tolerance.

Figure 3

(A) CF512 temperature-sensitive sterile worms were grown at 25 °C, and life span was monitored. Samples were taken at indicated times.

(B) DNA from CF512 temperature-sensitive sterile worms was extracted at the indicated time points, and telomere length was monitored in mixed and synchronous populations (for details, see Materials and Methods). Telomere length is indicated in kb. The asterisk points out a variable band-like signal resulting from gel drying.

(C) Seven different worm strains and daf-2 and daf-16 RNAi suppressed worms (indicated in different colors) with genetically determined telomere length (Figure 1D) were subjected to heat treatment as described [31]. Survival was assessed at the indicated time points.

(D) Two worm strains with long telomeres (CC2, TR403) and N2 worms with short telomeres were subjected to daf-16 suppression by RNAi. Life spans were determined as described.