Table 2.
Nodule counts (including all removed nodules at 24 mpt), diameter (means ± standard deviations) and median age scores of female worms before and 24 months after the start of treatment in cattle, following 7 monthly treatments with ivermectin 500 μg/kg subcutaneously, doramectin 500 μg/kg subcutaneously or no treatment. Nodule numbers were adjusted for nodules removed for assay. (the number of animals in each group, n = 3 except ‡ n = 2; number of nodules per group, n = 6 except * where n = 4).
| Timepoint | 0 mpt | 24 mpt | ||||
| count1 | Diameter2 (mm) | ♀age score3 | count | Diameter (mm) | ♀age score | |
| Control | 75 ± 26 | 5.9 ± 0.6 | 1.5 | 61 ± 25 ‡ | 6.7 ± 0.7* | 2* |
| Ivermectin | 73 ± 25 | 7.4 ± 1.2 | 1 | 72 ± 19 | 6.5 ± 0.4 | 3 |
| Doramectin | 73 ± 35 | 6.9 ± 1.1 | 2 | 66 ± 36 | 6.9 ± 0.9 | 3 |
1 Two-way ANOVA: effect of interaction of treatment and mpt p = 0.630; effect of treatment p = 0.891; effect of mpt p = 0.510
2 Two-way ANOVA: effect of interaction of treatment and mpt p = 0.270;effect of treatment p = 0.403; effect of mpt p = 0.996
3 Not tested statistically