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Structural Depiction of the different lengths of peptides and mutations in ssCGRP. (A) Structural depiction of CGRPR bound to αCGRP and G protein. (B) Structural depiction of the different lengths of peptides used throughout these studies. (C) The C-terminus of CGRP bound to CGRPR ECD (left). Model of the ssCGRP mutations (tan) in the C-terminus of the peptide bound to CGRPR ECD (right). All structural depictions were modeled and modified from PDB 6E3Y.
