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. 2025 Apr 7;42:102003. doi: 10.1016/j.bbrep.2025.102003

Fig. 5.

Fig. 5

Effect of MARK3 inhibition on CRPC and non-CRPC cell line

A. Representative images showing effect of PCC0208017 on the growth and viability of 22Rv1 cells 24, 48, and 72 h post-treatment with 0 nM, 10 nM, and 100 nM PCC0208017.

B. Bar plots representing the NucBlue intensity in 22Rv1 cells treated with varying concentrations of PCC0208017 at different time points.

C. Representative images showing effect of PCC0208017 on the growth and viability of PC3 cells 24, 48, and 72 h post-treatment with 0 nM, 10 nM, and 100 nM PCC0208017.

D. Bar plots representing the NucBlue intensity in PC3 cells treated with varying concentration of PCC0208017 at different time points.

E. Representative images showing the effect of PCC0208017 on migration potential of 22Rv1 cells treated with 0 nM, 10 nM, 50 nM, and 100 nM of PCC0208017.

F. Representative images showing the effect of PCC0208017 on migration potential of PC3 cells treated with 0 nM, 10 nM, 50 nM, and 100 nM of PCC0208017.

G. Bar plots representing the quantitation of migration potential of 22Rv1 cells treated with 0 nM, 10 nM, 50 nM, and 100 nM of PCC0208017.

H. Bar plots representing the quantitation of migration potential of PC3 cells treated with 0 nM, 10 nM, 50 nM, and 100 nM of PCC0208017.