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. 2025 Apr 17;25:719. doi: 10.1186/s12885-025-14133-9

Table 8.

Relationships between expression levels of glycolysis-related genes and the clinical parameters of cervical cancer patients

Characteristics, n = 300 ALDOA ENO3 GPI LDHA PGK1 PKM
high low p high low p high low p high low p high low p high low p
Histological classification < 0.001 < 0.001 < 0.001 0.03 0.03 < 0.001
 Squamous cell carcinoma 139 113 111 141 138 114 133 119 133 119 140 112
 Adeno-carcinoma 11 37 39 9 12 36 17 31 17 31 10 38
Primary tumor 0.03 0.45 0.003 0.29  < 0.001 0.51
 T1-T2 94 113 105 102 92 115 96 111 89 118 97 110
 T3-T4 20 10 13 17 22 8 17 13 24 6 16 14
Lymph node invasion 0.07 0.91 0.05 0.42 0.67 0.15
 N0 54 76 65 65 53 77 60 70 53 77 56 74
 N1 33 26 29 30 33 26 31 28 26 33 32 27
FIGO stage 0.01 0.65 0.03 0.07 0.01 0.17
 Stage I-II 103 125 116 112 105 123 108 120 105 123 108 120
 Stage III-IV 42 23 31 34 40 25 39 26 42 23 37 28
Treatment type 0.13 0.3 0.3 0.03 0.08 0.42
 Pharmaceutical Therapy, NOS 67 80 69 78 69 78 64 83 66 81 77 70
 Radiation Therapy, NOS 83 70 81 72 81 72 86 67 84 69 73 80

The chi-square tests were used for statistical analyses

Abbreviations: FIGO Federation International of Gynecology and Obstetrics