Table 8.
Relationships between expression levels of glycolysis-related genes and the clinical parameters of cervical cancer patients
| Characteristics, n = 300 | ALDOA | ENO3 | GPI | LDHA | PGK1 | PKM | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| high | low | p | high | low | p | high | low | p | high | low | p | high | low | p | high | low | p | |
| Histological classification | < 0.001 | < 0.001 | < 0.001 | 0.03 | 0.03 | < 0.001 | ||||||||||||
| Squamous cell carcinoma | 139 | 113 | 111 | 141 | 138 | 114 | 133 | 119 | 133 | 119 | 140 | 112 | ||||||
| Adeno-carcinoma | 11 | 37 | 39 | 9 | 12 | 36 | 17 | 31 | 17 | 31 | 10 | 38 | ||||||
| Primary tumor | 0.03 | 0.45 | 0.003 | 0.29 | < 0.001 | 0.51 | ||||||||||||
| T1-T2 | 94 | 113 | 105 | 102 | 92 | 115 | 96 | 111 | 89 | 118 | 97 | 110 | ||||||
| T3-T4 | 20 | 10 | 13 | 17 | 22 | 8 | 17 | 13 | 24 | 6 | 16 | 14 | ||||||
| Lymph node invasion | 0.07 | 0.91 | 0.05 | 0.42 | 0.67 | 0.15 | ||||||||||||
| N0 | 54 | 76 | 65 | 65 | 53 | 77 | 60 | 70 | 53 | 77 | 56 | 74 | ||||||
| N1 | 33 | 26 | 29 | 30 | 33 | 26 | 31 | 28 | 26 | 33 | 32 | 27 | ||||||
| FIGO stage | 0.01 | 0.65 | 0.03 | 0.07 | 0.01 | 0.17 | ||||||||||||
| Stage I-II | 103 | 125 | 116 | 112 | 105 | 123 | 108 | 120 | 105 | 123 | 108 | 120 | ||||||
| Stage III-IV | 42 | 23 | 31 | 34 | 40 | 25 | 39 | 26 | 42 | 23 | 37 | 28 | ||||||
| Treatment type | 0.13 | 0.3 | 0.3 | 0.03 | 0.08 | 0.42 | ||||||||||||
| Pharmaceutical Therapy, NOS | 67 | 80 | 69 | 78 | 69 | 78 | 64 | 83 | 66 | 81 | 77 | 70 | ||||||
| Radiation Therapy, NOS | 83 | 70 | 81 | 72 | 81 | 72 | 86 | 67 | 84 | 69 | 73 | 80 | ||||||
The chi-square tests were used for statistical analyses
Abbreviations: FIGO Federation International of Gynecology and Obstetrics