Table 1.

Use of Sepsis Definitions in Different Regions and Hospital Sizes and Types

	No. of Hospitals	Sepsis-1 Used	Sepsis-3 Used	Sepsis-1 and Sepsis-3 Used	Any Other Definition or No Definition Used
All hospitals	1,023	24.5% (21.9%–27.3%)	45.4% (42.3%–48.5%)	23.2% (20.6%–25.9%)	6.9% (5.5%–8.7%)
Region
Northern Europe	100	18.0% (11.0%–26.9%)	48.0% (37.9%–58.2%)	10.0% (4.9%–17.6%)	24.0% (16.0%–33.6%)
Eastern Europe	215	37.7% (31.2%–44.5%)	39.5% (33.0%–46.4%)	17.2% (12.4%–22.9%)	5.6% (2.9%–9.5%)
Southern Europe	185	22.7% (16.9%–29.4%)	53.5% (46.0%–60.9%)	20.0% (14.5%–26.5%)	3.8% (1.5%–7.6%)
Western Europe	335	18.2% (14.2%–22.8%)	43.0% (37.6%–48.5%)	33.4% (28.4%–38.8%)	5.4% (3.2%–8.4%)
Other regions	188	26.1% (19.9%–33.0%)	46.8% (39.5%–54.2%)	21.8% (16.1%–28.4%)	5.3% (2.6%–9.6%)
Hospital size
0–250 beds	295	29.8% (24.7%–35.4%)	40.7% (35.0%–46.5%)	24.4% (19.6%–29.7%)	5.1% (2.9%–8.2%)
251–500 beds	298	25.8% (21.0%–31.2%)	43.0% (37.3%–48.8%)	22.8% (18.2%–28.0%)	8.4% (5.5%–12.1%)
501–750 beds	157	22.3% (16.0%–29.6%)	47.1% (39.1%–55.2%)	22.3% (16.0%–29.6%)	8.3% (4.5%–13.7%)
751–1,000 beds	133	17.3% (11.3%–24.8%)	54.1% (45.3%–62.8%)	21.8% (15.1%–29.8%)	6.8% (3.1%–12.5%)
>1,000 beds	140	20.0% (13.7%–27.6%)	50.0% (41.4%–58.6%)	23.6% (16.8%–31.5%)	6.4% (3.0%–11.9%)
Hospital type
General hospitals	578	27.7% (24.1%–31.5%)	42.0% (38.0%–46.2%)	23.0% (19.6%–26.7%)	7.3% (5.3%–9.7%)
University hospitals	365	19.5% (15.5%–23.9%)	51.0% (45.7%–56.2%)	22.7% (18.5%–27.4%)	6.8% (4.5%–9.9%)
Independent hospitals	80	25.0% (16.0%–35.9%)	43.8% (32.7%–55.3%)	26.3% (17.0%–37.3%)	5.0% (1.4%–12.3%)

Data in parentheses are 95% CIs. “Sepsis-1” refers to the systemic inflammatory response syndrome criteria due to infection. “Sepsis-3” refers to new organ failure as evidenced by an increase in Sequential Organ Failure Assessment score by ≥2 due to infection.