TABLE 4:
Microtubule dynamics in HeLa cells. Values are mean ± 95% confidence interval. N = number of growing microtubules analyzed.
| Overexpressed β-tubulin | TUBB2b | TUBB3 | TUBB3:lat | TUBB3:I189V | TUBB3:T315A | TUBB3:V351T |
|---|---|---|---|---|---|---|
| N | 11613 | 10470 | 12752 | 13275 | 7009 | 10386 |
| Growth speed (µm/min) | 9.8 ± 0.1 | 9.9 ± 0.1 | 9.5 ± 0.1 | 10.2 ± 0.1 | 12.4 ± 0.2 | 10.16 ± 0.1 |
| Comet duration (seconds) | 27.4 ± 0.3 | 26.1 ± 0.7 | 27.2 ± 0.3 | 26.5 ± 0.3 | 25.5 ± 0.4 | 26.0 ± 0.3 |
| Growth events /µm2/min | 0.30 ± 0.04 | 0.34 ± 0.04 | 0.36 ± 0.03 | 0.40 ± 0.03 | 0.29 ± 0.04 | 0.38 ± 0.03 |
Values in boldface are significantly different from control cells expressing TUBB3 (p < 0.05).