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. 2025 Apr 13;20:1061–1070. doi: 10.2147/COPD.S485246

Table 3.

Exacerbation Management and Outcomes Stratified by Peripheral Eosinophils Less Than or Greater Than 2%

High Eosinophils
≥2%
n = 122
Low Eosinophils
<2%
n = 284
P value
Inpatient Management
 Antibiotics 84 (68.9) 234 (82.4) 0.002
 Systemic corticosteroids 97 (79.5) 216 (76.1) 0.448
  Oral corticosteroids 94 (77.0) 202 (71.1) 0.218
  Intravenous corticosteroids 21 (17.2) 65 (22.9) 0.200
 Oxygen 43 (35.2) 133 (46.8) 0.036
 ICU 6 (4.9) 18 (6.3) 0.578
 Non-invasive ventilation 5 (4.1) 14 (4.9) 0.711
 Invasive ventilation 1 (0.8) 0 (0.0) 0.127
Clinical Outcomes
 Length of stay, days 3.56 (3.05) 4.40 (4.23) 0.047
 Inpatient mortality 1 (0.8) 9 (3.2) 0.161
 12-month mortality 5 (4.1) 21 (7.4) 0.214

Note: Data presented as median (IQR) or number (%) unless otherwise indicated.

Abbreviations: ICU, intensive care unit.