Table 1.
Baseline demographic characteristics of the study patients.
| Variable | Total (n = 233) | CKD-495 75 mg (n = 52) | CKD-495 150 mg (n = 44) | Placebo (n = 47) | Stillen® 60 mg (n = 48) | Rebamipide100 mg (n = 42) | p value | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | |||||||||
| Sex | Men | 122 (52.7) | 25 (48.1) | 24 (54.6) | 32 (68.1) | 21 (43.8) | 20 (47.6) | 0.1396a | ||||||
| Women | 111 (47.6) | 27 (51.9) | 20 (45.5) | 15 (31.9) | 27 (56.3) | 22 (52.4) | ||||||||
|
| ||||||||||||||
| Age (yr) | Mean (±SD) | 48.61 (±16.4) | 45.12 (±14.5) | 48.43 (±16.6) | 51.38 (±17.4) | 47.40 (±17.3) | 51.43 (±16.5) | 0.2720b | ||||||
|
| ||||||||||||||
| Height (cm) | 165.60 (±8.75) | 165.92 (±8.79) | 165.99 (±9.2) | 166.96 (±8.0) | 164.92 (±9.0) | 164.06 (±8.8) | 0.6703a | |||||||
|
| ||||||||||||||
| Weight (kg) | 66.15 (±13.3) | 67.51 (±12.6) | 65.57 (±12.72) | 68.33 (±13.11) | 64.68 (±14.33) | 64.29 (±13.83) | 0.5334a | |||||||
|
| ||||||||||||||
| Concurrent disease | Present | 104 (44.6) | 22 (42.3) | 19 (43.2) | 21 (44.7) | 20 (41.7) | 22 (52.4) | 0.8541b | ||||||
|
| ||||||||||||||
| Past history | Present | 77 (33.1) | 15 (28.9) | 11 (25.0) | 20 (42.6) | 17 (35.4) | 14 (33.3) | 0.4416b | ||||||
|
| ||||||||||||||
| Concomitant medication | Present | 225 (96.57) | 51 (98.08) | 43 (97.73) | 44 (93.62) | 48 (100.00) | 39 (92.86) | 0.2655b | ||||||
|
| ||||||||||||||
| Gastrointestinal symptom scores | 4.99 (±2.9) | 4.6 (±3.1) | 4.75 (±2.9) | 5.11 (±2.6) | 5.13 (±3.1) | 5.45 (±3.0) | 0.6559 | |||||||
|
| ||||||||||||||
| Classification of gastritis | Acute gastritis | 72 | 30.9 | 18 | 34.62 | 11 | 25.00 | 14 | 29.79 | 13 | 27.08 | 16 | 38.10 | 0.6578a |
| Chronic gastritis | 161 | 69.1 | 34 | 65.38 | 33 | 75.00 | 33 | 70.21 | 35 | 72.92 | 26 | 61.90 | ||
|
| ||||||||||||||
| Duration of gastritis | Acute gastritis | 1.12 (±3.08) | 2.15 (±3.32) | 0.38 (±1.26) | 0 (±0.01) | 0.86 (±1.78) | 1.65 (±5.07) | 0.2854b | ||||||
| Chronic gastritis | 3.76 (±5.07) | 2.05 (±2.66) | 3.85 (±4.5) | 4.68 (±6.42) | 3.81 (±5.96) | 4.65 (±4.71) | 0.2175b | |||||||
Note: Data are presented as mean ± SD or number (%).
aChi-square test for intergroup comparison.
bAnalysis of variance for intergroup comparison.