Table 2.
Comparison of cost for rasburicase and allopurinol/sodium bicarbonate
Drug | Average dose per day | Maximum duration | Cost per day* | Cost of 5 days of therapy |
Allopurinol sodium (intravenous) | 300 mg | NA | $473.89 | $2369.45 |
Oral allopurinol | 600 mg | NA | $0.28 | $1.40 |
Sodium bicarbonate intravenous (90 mEq)‡ | 4000 ml (rate, 150–200 mL/h) | NA | $0.74 | $29.60 |
Rasburicase | 13.5 mg‡ (based on 0.2 mg/kg for 70-kg patient) | 5 days | $2724.84 | $13, 624.20 |
NA indicates not applicable.
*Cost is based on Baylor University Medical Center's pharmacy acquisition cost.
†Mixed with 1000-mL dextrose 5% in water (D5W). The cost figures given exclude the D5W bag.
‡Dose is rounded to the nearest vial size.