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. 2025 Apr 9;53:101295. doi: 10.1016/j.lanepe.2025.101295

Table 1.

Top 30 level-3 causes of years lived caregiving for older relatives (YLCs) in Europe.

Years lived caregiving (YLC) rate per 100,000
2000 2021 2050 Change
2021 versus 2000 2050 versus 2000
1. Low back pain 262 (251–274) 300 (288–312) 326 (313–338) 14.6% (10–19.7) 24.4% (19.1–29.9)
2. Diabetes mellitus 101 (95.2–106) 162 (155–169) 252 (242–261) 61% (52.5–70.1) 150% (138–164)
3. Falls 150 (144–156) 182 (174–191) 227 (215–239) 21.4% (16.5–26.1) 51.2% (45–57.9)
4. Age-related and other hearing loss 130 (125–137) 167 (160–173) 220 (212–229) 27.9% (23.6–32.7) 69% (63.1–75.4)
5. Alzheimer’s disease and other dementias 82.1 (74.5–90.4) 121 (112–132) 184 (170–201) 47.6% (32.5–62.4) 125% (100–150)
6. Osteoarthritis 107 (103–112) 135 (129–140) 161 (155–167) 25.7% (21–30.6) 50.4% (43.4–56.6)
7. Oral disorders 89.6 (86.3–93) 99.7 (95.9–104) 119 (115–124) 11.4% (7.52–15.3) 33.3% (28.3–38.3)
8. Depressive disorders 90.6 (83.6–98) 110 (103–119) 113 (105–122) 21.9% (10.1–33) 25.3% (13.8–38)
9. Blindness and vision loss 64.1 (59.8–68.3) 76.9 (72.5–81.7) 96.2 (90.3–102) 19.9% (12.2–28.5) 50.1% (40.7–61.8)
10. Stroke 63.3 (57.6–68.6) 68.4 (61.9–74.4) 91.1 (83.9–98.9) 8.16% (−4.76 to 22) 44% (30.1–61.4)
11. Chronic obstructive pulmonary disease 46.2 (43.5–49.1) 59.5 (55.9–63.1) 83.7 (78.9–88.3) 28.8% (20.4–38.1) 81.3% (70.4–94.4)
12. Anxiety disorders 64.9 (59.3–70.4) 85.2 (78.8–92.1) 81.6 (75.8–87.8) 31.5% (19.5–45.2) 26.1% (14.1–41)
13. Other musculoskeletal disorders 47.9 (43.5–51.9) 61.6 (57.5–65.4) 74.2 (69.9–79.6) 28.8% (16.8–40.5) 55.3% (40.4–75.2)
14. Chronic kidney disease 29.7 (27.7–31.9) 40.8 (38.2–43.4) 72.4 (67.2–77.2) 37.6% (27.4–48.5) 144% (127–165)
15. Headache disorders 66.1 (62.8–69.1) 73.1 (69.7–76.3) 71.8 (68.6–74.8) 10.6% (4.9–17.2) 8.55% (2.19–13.8)
16. Atrial fibrillation and flutter 33.6 (30.5–36.4) 42 (38.9–45.4) 61.5 (57.2–66) 25.4% (12.7–39.6) 83.7% (64.1–106)
17. Neck pain 50.8 (46.6–55.1) 57.7 (53.1–62.3) 61 (56.8–65.5) 13.7% (3.62–26.4) 20.2% (8.48–32.3)
18. Other cardiovascular and circulatory diseases 36.4 (33.3–39.7) 47.1 (43.3–50.7) 58.8 (54.5–63.2) 29.5% (16.1–41) 61.8% (45.3–77.8)
19. Ischemic heart disease 28.2 (26.7–30) 31.1 (29–33) 41.8 (39.5–44.2) 10.1% (2.08–18.4) 48% (38.2–58)
20. Gynecological diseases 40 (37.9–42.4) 42.8 (40.4–45.3) 37.8 (34.7–41.3) 7.11% (−0.225 to 14.9) −5.26% (−14.1 to 3.74)
21. Gallbladder and biliary diseases 29.3 (27.7–30.8) 30.7 (29.2–32.5) 34.3 (32.4–36.3) 5.14% (−1.36 to 12.8) 17.4% (9.24–26.4)
22. Exposure to mechanical forces 28.6 (27.1–30.1) 28.1 (26.8–29.4) 28.8 (27.4–30.1) −1.84% (−7.47 to 3.67) 0.698% (−4.37 to 6.93)
23. Alcohol use disorders 22.6 (20.3–25.3) 24.2 (21.6–26.7) 25.4 (23.1–28.2) 7.06% (−6.18 to 22.1) 12.7% (−1.36 to 30.8)
24. Other mental disorders 18.9 (16.9–21) 21.9 (20–24.2) 24.3 (22.3–26.7) 16.5% (1.69–33.3) 29.3% (13.6–45.4)
25. Road injuries 34.3 (31.8–36.9) 21.1 (19.4–23) 22.3 (20.7–24.3) −38.5% (−44.2 to −32.2) −35% (−41.1 to −27.5)
26. Other sense organ diseases 15.1 (13.9–16.6) 18.4 (17.2–19.8) 22 (20.3–23.7) 22.1% (11–35.3) 46.1% (30.3–62.3)
27. Bipolar disorder 18.9 (15.6–22.7) 21.6 (18.4–25.5) 21.9 (18.3–25.1) 15.5% (−10.9 to 45.2) 17% (−6.53 to 44.6)
28. Schizophrenia 19.4 (14.1–25.1) 21.3 (15.6–27.5) 21 (15.8–27.2) 12% (−25.5 to 61.7) 10.6% (−27.1 to 65.8)
29. Parkinson’s disease 9.96 (7.67–12) 14.4 (12.2–16.8) 20.7 (17.6–23.6) 46.5% (14.2–94) 110% (61.8–175)
30. Prostate cancer 9.16 (7.49–10.7) 12 (10.4–13.9) 20.5 (17.9–22.8) 32% (6.75–62.7) 125% (84.6–181)

Health conditions are sorted by 2050 rates. The numbers between brackets are the 95% UIs. The full list of causes is provided in the Supplementary appendix (pp. 58–67).