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Modeling of DNA/nanoparticle conjugates. (a) A 19-residue duplex DNA molecule and 0.8-, 1.2-, and 10-nm-diameter gold particles drawn to scale. (b) Scale drawing as in a, illustrating partial swept volumes for two, three, and four DNA molecules in colinear, trigonal planar, and tetrahedral arrangements. See Tables 1-3, which are published as supporting information on the PNAS web site, for the Protein Data Bank coordinates for these models.
