Skip to main content
. 2025 Feb 27;222(7):334–336. doi: 10.5694/mja2.52618
Without iron overload With iron overload

Infections

Hereditary haemochromatosis (HFE haemochromatosis and non‐HFE haemochromatosis)
Acute
Chronic
Metabolic syndrome

Iatrogenic

Excess iron supplementation (oral and/or intravenous)
Frequent/excess blood transfusions
Alcohol excess Haemoglobinopathies/iron loading anaemias
Liver disease (metabolic dysfunction‐associated steatotic liver disease, viral hepatitis, other) Porphyria cutanea tarda

Inflammatory conditions

Other genetic causes (aceruloplasminaemia)
Rheumatological and immunological conditions
Malignancy
Thyrotoxicosis