Table 3.

Multiple linear regression analysis of each factor and C/D

Item	A				B				C				D
	Estimated value	Standard error	t	P	Estimated value	Standard error	t	P	Estimated value	Standard error	t	P	Estimated value	Standard error	t	P
Weight	1.38	0.33	4.13	< 0.0001**	1.23	0.31	3.99	0.0001**					0.69	0.23	2.98	0.0037**
Surface area	− 69	16.64	− 4.15	< 0.0001**	− 60.28	14.94	− 4.03	< 0.0001**					− 31.15	11.32	− 2.75	0.0072**
PLT									0.01	0.01	2.17	0.0322*
AST	0.29	0.1	2.99	0.0032**
ALT	− 0.12	0.05	− 2.3	0.0226*
ALB	− 0.54	0.25	− 2.15	0.0333*	− 0.99	0.28	− 3.57	0.0005**

Group A, B, C, and D: 1week after sirolimus (group A), 2 weeks after sirolimus (group B), 4 weeks after sirolimus(group C), and 12 weeks after sirolimus (group D)

*The multiple linear regression analysis revealed a significant relationship between X and the corrected sirolimus C/D

t t-value, P P-value, PLT platelet count, AST aspartate aminotransferase, ALT alanine aminotransferase, TBIL total bilirubin, ALB albumin