FIG. 2.

flake mutant mice develop persistent skin infections when exposed to gram-positive bacteria. (A and B) Time course analyses of the bacterial growth in control (C57BL/6) (n = 4) and mutant (flake/flake) (n = 4) animals subcutaneously infected with S. pyogenes (A) or S. aureus (B). (Upper panels) Graphs show results of quantification by luminescence (expressed as a percentage of the luminescence in the initial inoculum) for four animals of each genotype. (Lower panels) Overlay of photographs and light detection for two representative mice for each genotype at the indicated days after inoculation. (C) Infection with E. coli.