FIG. 3.

Dexamethasone decreases innate resistance to intestinal E. histolytica infection in susceptible strains. CBA, C3H/HeJ, C3H SCID, and C57BL/6 mice were treated with 0.2 mg dexamethasone (Dex) or PBS on days −3, −2, −1, and 0 relative to intracecal challenge. The proportions of mice infected upon sacrifice are shown (n = 15, n = 20, n = 34, n = 29, n = 9, n = 8, n = 6, and n = 8 for the groups shown from left to right on the x axis) An asterisk indicates that the P value is ≤0.05 compared with PBS-treated mice. C3H/HeJ mice were sacrificed at 30 days postchallenge, and all other mice were sacrificed at 10 days postchallenge.