Table 2.
Frequency of positive VZV-specific IgG and neutralizing antibodies in the elderly and adult comparison group.
| Serostatus | All participants (N = 235) |
Adult (N = 22) |
Elderly (N = 213) |
p-value |
|---|---|---|---|---|
| VZV gp IgG ELISA, N (%) | < 0.001 | |||
| Seropositive | 229 (97.4) | 19 (86.4) | 210 (98.6) | |
| Borderline | 2 (0.9) | 0 (0.0) | 2 (0.9) | |
| Seronegative | 4 (1.7) | 3 (13.6) | 1 (0.5) | |
| VZV live virus MNT, N (%) | < 0.001 | |||
| Detectable NAb titer | 148 (63.0) | 6 (27.3) | 142 (66.7) | |
| Undetectable NAb titer | 87 (37.0) | 16 (72.7) | 71 (33.3) |
Undetectable NAb titer was no detectable inhibition at the lowest dilution (1:20).
Pearson Chi-Square test was used to test the differences between adult and elderly groups.
Bold p-values indicate statistical difference (p < 0.05).
MNT microneutralization test, Nab neutralizing antibody.