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IL-2 profiles of bovine PBMCs from noninfected cattle and low and medium shedders after stimulation with recombinant antigens for 24 h. Results represent the mean fold increases of IL-2 over unstimulated PBMCs, which served as calibrators. Ags 85A and 85B most strongly stimulated medium shedders, while the 35-kDa protein and SOD had lesser effects (P < 0.05).
