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. 2005 Aug;73(8):4704–4713. doi: 10.1128/IAI.73.8.4704-4713.2005

TABLE 2.

Putative function, amino acid number, and related proteins in GenBank database for antigens identified with a single rabbit antiserum (antigens 1 to 28) or with more than one antiserum (antigens 29 to 36)

Antigen GenBank accession no. and organism Descriptiona(reference) No. of amino acidsa Putative functiona Serum usedb
1 AAK49451, A. fumigatus Enolase (27) 438 Carbohydrate transport and metabolism 2a, 2b
2 EAA65375, A. nidulans Histone H3 141 Histone 2a
3 EAA63190, A. nidulans Putative Sla2 protein (yeast) 967 Cytoskeleton assembly control 2a
4 EAA57767, A. nidulans Putative Acyl CoA binding proteind 144 Lipid metabolism 2b
5 EAA61425, A. nidulans Putative cation exchanger 742 Sodium/calcium exchanger; integral membrane protein 2b
6 CAF32126, A. fumigatus Putative nuclear segregation protein (40) 510 Mitosis and vesicular transport 2b
7 EAA60966, A. nidulans Pyruvate decarboxylase 585 Carbohydrate transport and metabolism 2b
8 EAA57865, A. nidulans Formate dehydrogenase 377 Energy production and conversion 2b
9 EAA63885, A. nidulans Bromo domain containing protein 312 Unknown 3a
10 EAA61085, A. nidulans Protein containing class II aldolase/adducin domain 312 Possibly carbohydrate metabolism 3a
11 EAA59042, A. nidulans Hypothetical protein 106 Unknown 3a
12 EAA62389, A. nidulans Hypothetical protein with chromosome segregation ATPase-containing region 779 Cell division and chromosome partitioning 3a
13 EAA61660, A. nidulans Hypothetical protein with a region of the superfamily I DNA and RNA helicases and helicases subunit 1,162 Possibly DNA replication, recombination, and repair 3a
14 EAA60227, A. nidulans Putative pyruvate carboxylase 1,196 Carbohydrate transport and metabolism 3b
15 EAA65951, A. nidulans Hypothetical protein with similarities to archain 1 (yeast) 516 Intracellular vesicle mediated transport 3b
16 EAA63693, A. nidulans Hypothetical protein with a tetratricopeptide repeat domain 576 Unknown 3b
17 EAA63343, A. nidulans Hypothetical protein with DnaJ molecular chaperone homology domain 466 Unknown 3b
18 EAA62238, A. nidulans Hypothetical protein with region similar to chromosome segregation ATPases 941 Possibly cell division and chromosome partitioning 4a 4b
19 EAA59763, A. nidulans HSP 30 180 Heat shock protein, chaperone 4a
20 CAA75754, A. fumigatus PEP2 (A1) cellular aspartic protease (42) 398 Protein turnover (vacuole) 4a
21 EAA58700, A. nidulans Hypothetical protein with regions homologous to DNA mismatch repair enzyme PMS1 (yeast) 1,228 Probably DNA replication, recombination, and repair 4b
22 EAA66952, A. nidulans Hypothetical protein; putative choline dehydrogenase 631 Amino acid transport and metabolism 5
23 EAA66888, A. nidulans Hypothetical protein; contains a signal for secretion 305 Unknown 5
24 EAA64755, A. nidulans Hypothetical protein, contains similarity to PRP39 (yeast) 588 Possibly pre-mRNA 3′ end processing 6
25 EAA58305, A. nidulans Hypothetical protein with a WD40 domain and homology to PRP19/PSO4 (yeast) 475 Pre-mRNA processing 6
26 EAA64758, A. nidulans Hypothetical protein with similarity to aminopeptidase N (M1) 883 Protein turnover 6
27 EAA59355, A. nidulans Hypothetical protein with similarity to sterol C14-reductase 496 Ergosterol biosynthesis 6
28 EAA58058, A. nidulans Ribosomal L10 protein 250 Ribosome (mRNA-directed protein synthesis) 6
29 CAF32073, A. fumigatus Putative transketolase (40) 689 Carbohydrate transport and metabolism 1, 6
30 EAA58837, A. nidulans Hypothetical protein 1,157 Unknown 2ac, 4bc
31 AAB51544, A. fumigatus;EAA59007, A. nidulans HSP90 (25) 441 (partial);700 Heat shock protein, chaperone 2a, 2b, 5
32 O43099, A. fumigatus AHP1 = allergen Asp f 3 (= PMP20) (23), peroxiredoxin family reductase 168 Antioxidant, probable peroxisomal membrane protein 2a, 2b, 5
33 CAF31979, A. fumigatus Putative HSP88 (40) 714 Heat shock protein, chaperone 3bc, 4a
34 EAA57903, A. nidulans Probable translation elongation factor 1 411 translation 1c, 5, 6
35 EAA63438, A. nidulans Phosphoglucomutase 556 Carbohydrate transport and metabolism 2b, 5, 6
36 CAA11266, AAC61261, AAN87849, A. fumigatus Allergen Asp f 9 (13), allergen Asp f 16 (2), CRH-like protein 302, 427, 395 Glycosidase / cell wall metabolism 2b, 5, 6
a

Descriptions are based on homologues that are described for A. fumigatus, A. nidulans, or yeast (S. cerevisiae) that were found in BLAST searches, performed August 2004.

b

Serum identifiers are listed in Table 1.

c

Showed weak reactivity with preinfection serum. All other antigens showed no detectable reactivity with preinfection serum from responding rabbits.

d

Acyl CoA, acyl coenzyme A.