TABLE 2.
Antigen | GenBank accession no. and organism | Descriptiona(reference) | No. of amino acidsa | Putative functiona | Serum usedb |
---|---|---|---|---|---|
1 | AAK49451, A. fumigatus | Enolase (27) | 438 | Carbohydrate transport and metabolism | 2a, 2b |
2 | EAA65375, A. nidulans | Histone H3 | 141 | Histone | 2a |
3 | EAA63190, A. nidulans | Putative Sla2 protein (yeast) | 967 | Cytoskeleton assembly control | 2a |
4 | EAA57767, A. nidulans | Putative Acyl CoA binding proteind | 144 | Lipid metabolism | 2b |
5 | EAA61425, A. nidulans | Putative cation exchanger | 742 | Sodium/calcium exchanger; integral membrane protein | 2b |
6 | CAF32126, A. fumigatus | Putative nuclear segregation protein (40) | 510 | Mitosis and vesicular transport | 2b |
7 | EAA60966, A. nidulans | Pyruvate decarboxylase | 585 | Carbohydrate transport and metabolism | 2b |
8 | EAA57865, A. nidulans | Formate dehydrogenase | 377 | Energy production and conversion | 2b |
9 | EAA63885, A. nidulans | Bromo domain containing protein | 312 | Unknown | 3a |
10 | EAA61085, A. nidulans | Protein containing class II aldolase/adducin domain | 312 | Possibly carbohydrate metabolism | 3a |
11 | EAA59042, A. nidulans | Hypothetical protein | 106 | Unknown | 3a |
12 | EAA62389, A. nidulans | Hypothetical protein with chromosome segregation ATPase-containing region | 779 | Cell division and chromosome partitioning | 3a |
13 | EAA61660, A. nidulans | Hypothetical protein with a region of the superfamily I DNA and RNA helicases and helicases subunit | 1,162 | Possibly DNA replication, recombination, and repair | 3a |
14 | EAA60227, A. nidulans | Putative pyruvate carboxylase | 1,196 | Carbohydrate transport and metabolism | 3b |
15 | EAA65951, A. nidulans | Hypothetical protein with similarities to archain 1 (yeast) | 516 | Intracellular vesicle mediated transport | 3b |
16 | EAA63693, A. nidulans | Hypothetical protein with a tetratricopeptide repeat domain | 576 | Unknown | 3b |
17 | EAA63343, A. nidulans | Hypothetical protein with DnaJ molecular chaperone homology domain | 466 | Unknown | 3b |
18 | EAA62238, A. nidulans | Hypothetical protein with region similar to chromosome segregation ATPases | 941 | Possibly cell division and chromosome partitioning | 4a 4b |
19 | EAA59763, A. nidulans | HSP 30 | 180 | Heat shock protein, chaperone | 4a |
20 | CAA75754, A. fumigatus | PEP2 (A1) cellular aspartic protease (42) | 398 | Protein turnover (vacuole) | 4a |
21 | EAA58700, A. nidulans | Hypothetical protein with regions homologous to DNA mismatch repair enzyme PMS1 (yeast) | 1,228 | Probably DNA replication, recombination, and repair | 4b |
22 | EAA66952, A. nidulans | Hypothetical protein; putative choline dehydrogenase | 631 | Amino acid transport and metabolism | 5 |
23 | EAA66888, A. nidulans | Hypothetical protein; contains a signal for secretion | 305 | Unknown | 5 |
24 | EAA64755, A. nidulans | Hypothetical protein, contains similarity to PRP39 (yeast) | 588 | Possibly pre-mRNA 3′ end processing | 6 |
25 | EAA58305, A. nidulans | Hypothetical protein with a WD40 domain and homology to PRP19/PSO4 (yeast) | 475 | Pre-mRNA processing | 6 |
26 | EAA64758, A. nidulans | Hypothetical protein with similarity to aminopeptidase N (M1) | 883 | Protein turnover | 6 |
27 | EAA59355, A. nidulans | Hypothetical protein with similarity to sterol C14-reductase | 496 | Ergosterol biosynthesis | 6 |
28 | EAA58058, A. nidulans | Ribosomal L10 protein | 250 | Ribosome (mRNA-directed protein synthesis) | 6 |
29 | CAF32073, A. fumigatus | Putative transketolase (40) | 689 | Carbohydrate transport and metabolism | 1, 6 |
30 | EAA58837, A. nidulans | Hypothetical protein | 1,157 | Unknown | 2ac, 4bc |
31 | AAB51544, A. fumigatus;EAA59007, A. nidulans | HSP90 (25) | 441 (partial);700 | Heat shock protein, chaperone | 2a, 2b, 5 |
32 | O43099, A. fumigatus | AHP1 = allergen Asp f 3 (= PMP20) (23), peroxiredoxin family reductase | 168 | Antioxidant, probable peroxisomal membrane protein | 2a, 2b, 5 |
33 | CAF31979, A. fumigatus | Putative HSP88 (40) | 714 | Heat shock protein, chaperone | 3bc, 4a |
34 | EAA57903, A. nidulans | Probable translation elongation factor 1 | 411 | translation | 1c, 5, 6 |
35 | EAA63438, A. nidulans | Phosphoglucomutase | 556 | Carbohydrate transport and metabolism | 2b, 5, 6 |
36 | CAA11266, AAC61261, AAN87849, A. fumigatus | Allergen Asp f 9 (13), allergen Asp f 16 (2), CRH-like protein | 302, 427, 395 | Glycosidase / cell wall metabolism | 2b, 5, 6 |
Descriptions are based on homologues that are described for A. fumigatus, A. nidulans, or yeast (S. cerevisiae) that were found in BLAST searches, performed August 2004.
Serum identifiers are listed in Table 1.
Showed weak reactivity with preinfection serum. All other antigens showed no detectable reactivity with preinfection serum from responding rabbits.
Acyl CoA, acyl coenzyme A.