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Real-time PCR for detection of O. tsutsugamushi after challenge in infected and vaccinated monkeys (phase III)
| Animal IDa | Dose of challenge (MuLD50) | Detection of O. tsutsugamushi in blood collected on given day after challengeb
|
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 4 | 6 | 8 | 11 | 13 | 15 | 18 | 20 | 22 | 25 | ||
| 1 | 106 | − | − | − | − | − | − | |||||
| 3 | 106 | − | − | − | − | − | − | |||||
| 5 | 106 | − | + | + | + | + | + | − | − | − | − | − |
| 6 | 106 | − | + | + | + | + | + | + | − | − | − | − |
Animals 1 and 3 were infected, while animals 5 and 6 were vaccinated.
+, positive; −, negative.
