Table 3.
Multivariable Adjusted Association of BMI Category with Mortality in Younger- and Older-Onset Diabetes, Stratified by Race
| Young-Onset | Older-Onset | |||
|---|---|---|---|---|
| African Americans | Whites | African Americans | Whites | |
| HR (95% CI) | HR (95% CI) | HR (95% CI) | ||
| BMI category, kg/m2 | ||||
| <25 | Ref | Ref | Ref | Ref |
| 25–29.9 | 0.73 (0.54–1.00) | 0.55 (0.34–0.90) | 0.70 (0.63–0.77) | 0.86 (0.73–1.02) |
| 30–34.9 | 0.82 (0.60–1.15) | 0.62 (0.37–1.06) | 0.65 (0.58–0.72) | 0.99 (0.84–1.17) |
| 35–39.9 | 0.67 (0.47–0.96) | 0.51 (0.28–0.92) | 0.76 (0.68–0.85) | 1.04 (0.87–1.24) |
| ≥40 | 0.78 (0.55–1.11) | 0.98 (0.58–1.67) | 0.95 (0.85–1.07) | 1.45 (1.22–1.73) |
| Sex, female | 0.62 (0.50–0.77) | 0.60 (0.42–0.85) | 0.60 (0.56–0.65) | 0.69 (0.63–0.76) |
| Diabetes duration | 0.94 (0.93–0.95) | 0.95 (0.93–0.96) | 1.00 (1.00–1.00) | 1.00 (1.00–1.01) |
| Hypercholesterolemia | ||||
| No | Ref | Ref | Ref | Ref |
| Treated | 0.99 (0.79–1.23) | 1.07 (0.74–1.56) | 0.82 (0.77–0.88) | 0.69 (0.62–0.77) |
| Not treated | 0.98 (0.75–1.28) | 1.08 (0.65–1.80) | 0.95 (0.86–1.04) | 0.85 (0.73–0.98) |
| Hypertension | 1.11 (0.88–1.41) | 1.63 (1.07–2.47) | 1.05 (0.96–1.15) | 0.99 (0.88–1.12) |
| Hx of CHD | 1.34 (1.05–1.72) | 1.56 (1.08–2.26) | 1.38 (1.26–1.50) | 1.32 (1.18–1.47) |
| Hx of TIA/stroke | 1.30 (1.01–1.67) | 1.03 (0.68–1.57) | 1.30 (1.19–1.42) | 1.22 (1.07–1.39) |
| Hx of smoking | 1.15 (0.94–1.41) | 2.17 (1.47–3.21) | 1.48 (1.39–1.59) | 1.61 (1.45–1.79) |
| <high school graduate | 0.97 (0.72–1.31) | 1.49 (0.91–2.44) | 0.73 (0.66–0.80) | 0.93 (0.81–1.07) |
| Household income <$15,000/yr | 1.48 (1.18–1.84) | 1.21 (0.84–1.75) | 1.40 (1.30–1.50) | 1.62 (1.46–1.79) |
| Health insurance | 1.18 (0.95–1.46) | 0.82 (0.57–1.18) | 0.78 (0.72–0.83) | 0.64 (0.57–0.71) |
| BMI by race p-interaction = 0.24 | BMI by race p-interaction = 0.0001 | |||