TABLE 3.
Mean inflammatory marker concentrations and difference from the mean for each 1% of membrane fatty acids from trans fatty acids (TFAs)1
| Concentration2 | Partial correlation coefficient | Difference from mean3 | Percentage difference3 | P | |
|---|---|---|---|---|---|
| % | |||||
| IL-1β (pg/mL) | 0.57 ± 0.08 | 0.26 | 0.38 | 66 | 0.04 |
| IL-1 receptor α (pg/mL) | 1360 ± 358 | 0.34 | 4033 | 297 | 0.006 |
| IL-6 (pg/mL) | 7.7 ± 1.7 | 0.35 | 9.5 | 123 | 0.006 |
| IL-10 (pg/mL) | 132 ± 32 | 0.31 | 241 | 183 | 0.02 |
| TNF-α (pg/mL) | 103 ± 30 | 0.30 | 256 | 249 | 0.02 |
| TNF receptor 1 (pg/mL) | 1322 ± 91 | 0.28 | 537 | 41 | 0.03 |
| TNF receptor 2 (pg/mL) | 15 880 ± 4347 | 0.43 | 39242 | 247 | 0.001 |
| MCP-1 (pg/mL) | 98 ± 19 | 0.36 | 117 | 119 | 0.004 |
| BNP (pg/mL) | 71 ± 7 | 0.24 | 40 | ± 57 | 0.04 |
| Soluble IL-6 receptor (pg/mL) | 14 432 ± 566 | −0.18 | −1869 | −13 | 0.18 |
| IL-8 (pg/mL) | 9.7 ± 0.9 | 0.09 | 2.2 | 23 | 0.33 |
| Endothelin-1 (pg/mL) | 2.0 ± 0.1 | −0.10 | −0.18 | −9 | 0.42 |
| TGF-β (pg/mL) | 13 560 ± 1306 | −0.19 | −3855 | −28 | 0.17 |
| CRP (mg/L) | 5.7 ± 0.9 | −0.23 | −2.7 | −48 | 0.05 |
| SAA (pg/mL) | 9.0 ± 1.8 | −0.24 | −3.9 | −44 | 0.06 |
1
BNP, brain natriuretic peptide; CRP, C-reactive protein; IL, interleukin; MCP-1, monocyte chemoattractant protein 1; SAA, serum amyloid A; TGF, transforming growth factor; TNF, tumor necrosis factor.
2
All values are x¯ ± SEM.
3
Differences are approximately those between the first and third TFA tertile means, adjusted for age, sex, BMI, smoking, ejection fraction, New York Heart Association class, ischemic etiology, statin use, and serum glucose.