Skip to main content
. 2025 Apr 15;2025:4867529. doi: 10.1155/sci5/4867529

Table 2.

Percentage of biofilm formation inhibition by tested agents against Streptococcus species.

Agent Concentration Biofilm inhibition (%)
S. mutans ATCC 25175 S. mutans clinical no. 5 S. mutans clinical no. 15 S. mutans clinical no. 31 S. mitis ATCC 49456 S. salivarius ATCC 9759
C. asiatica extract 1/8 × MIC 25.30 ± 1.2 22.23 ± 0.9 20.70 ± 1.8 16.07 ± 1.0 20.20 ± 1.2 23.97 ± 1.8
1/4 × MIC 40.80 ± 1.8 35.27 ± 1.3 35.97 ± 1.2 34.37 ± 0.9 31.33 ± 1.0 36.43 ± 1.2
1/2 × MIC 55.60 ± 1.0 45.17 ± 0.8 46.93 ± 1.0 41.77 ± 1.2 46.60 ± 1.4 53.57 ± 1.1

Synthesized AgNPs 1/8 × MIC 45.20 ± 1.4 46.27 ± 1.2 47.20 ± 1.8 39.63 ± 1.6 39.07 ± 1.4 35.10 ± 1.0
1/4 × MIC 63.90 ± 0.9 59.50 ± 1.4 60.67 ± 1.2 57.70 ± 0.7 62.27 ± 1.8 63.33 ± 1.8
1/2 × MIC 78.40 ± 1.2 77.53 ± 1.8 75.43 ± 0.9 76.03 ± 1.2 71.57 ± 0.9 75.17 ± 1.2

Asiatic acid 1/8 × MIC 18.40 ± 1.0 17.03 ± 1.1 16.30 ± 1.6 13.47 ± 1.8 17.83 ± 1.2 13.60 ± 0.8
1/4 × MIC 32.80 ± 1.8 28.20 ± 0.9 32.47 ± 1.2 20.83 ± 1.0 24.70 ± 1.0 21.30 ± 0.9
1/2 × MIC 47.10 ± 1.1 42.93 ± 1.0 39.07 ± 1.6 19.83 ± 0.9 33.03 ± 1.2 37.80 ± 1.4

Madecassic acid 1/8 × MIC 16.50 ± 0.9 15.23 ± 1.2 15.33 ± 0.7 17.00 ± 1.4 14.95 ± 1.1 14.57 ± 1.2
1/4 × MIC 28.30 ± 1.2 24.77 ± 1.8 25.80 ± 1.0 19.83 ± 1.2 29.27 ± 1.8 27.03 ± 1.0
1/2 × MIC 39.70 ± 1.8 35.37 ± 1.0 30.30 ± 1.8 20.33 ± 0.9 35.20 ± 1.2 36.03 ± 1.0

AgNPs control 18.57 ± 0.9 17.10 ± 1.4 15.74 ± 1.2 17.06 ± 1.4 17.78 ± 1.1 17.63 ± 0.9

0.2% chlorhexidine 82.03 ± 1.2 78.97 ± 1.8 77.99 ± 0.9 77.33 ± 1.6 81.03 ± 1.8 83.30 ± 1.2

Note: Data are presented as the mean ± SE from three independent experiments.