Table 2.

Histological alterations considered for the assignment of the liver condition indexes score

Liver condition index	Histological alteration
Circulatory disturbance	Sinusoid congestion
	Blood vessel congestion
	Hemorrhages
Regressive changes	Mild lipid accumulation
	Severe lipid accumulation
	Pycnotic nuclei
	Cord loss
	Vacuolar tissue degeneration
Progressive changes	Tissue necrosis
	Hepatocytes hyperplasia
	Hepatocytes hypertrophy
	Bile duct hypertrophy
Granulocytes infiltration	Scattered cells
	Tightly aggregated cells