Table 3.
Results from hepatocytes number and peripheral nuclei per area quantification and liver condition evaluation in terms of circulatory disturbance, regressive and progressive changes and granulocyte infiltration in liver from the different experimental groups. Data are reported as mean of the observation. Different letters indicate statistically significant differences among the groups (a,b; p < 0.05)
| HI0 | HI25 | HI35 | HI50 | p-value | |
|---|---|---|---|---|---|
| Hepatocytes (n/0.3 mm2) | 324.9 ± 34.6a | 286.9 ± 33.7ab | 271.1 ± 32.0ab | 263.7 ± 32.4b | 0.029 |
| Peripheral nuclei (n/0.3 mm2) | 277.6 ± 37.4 | 253.9 ± 31.2 | 241.5 ± 26.7 | 227.8 ± 34.9 | 0.101 |
| Circulatory disturbance (score) | 1.45 ± 0.37 | 1.75 ± 0.94 | 0.67 ± 0.88 | 2.04 ± 1.08 | 0.068 |
| Regressive changes (score) | 1.90 ± 0.42 | 2.17 ± 0.52 | 1.50 ± 0.55 | 2.29 ± 0.57 | 0.068 |
| Progressive changes (score) | 1.80 ± 0.67 | 2.17 ± 0.52 | 1.58 ± 0.58 | 1.64 ± 0.63 | 0.347 |
| Granulocyte infiltration (score) | 0.650 ± 0.602b | 2.000 ± 0.791a | 0.583 ± 0.563b | 1.107 ± 0.453ab | 0.003 |