Table 1.
Expression patterns of co-stimulatory molecules of CD11cmidCD206-CD11b+ interstitial macrophage (IM) subpopulations.
| Sham | LPS | CIA | CIA+LPS | |
|---|---|---|---|---|
| MHChiLy6Chi | ||||
| CD80+ | 0.033 (0.017) | 0.102 (0.069)# | 0.118 (0.068)# | 0.401 (0.110)#,*,† |
| CD86+ | 0.035 (0.021) | 0.139 (0.108)# | 0.152 (0.110)# | 0.539 (0.477)#,† |
| CD80+CD86+ | 0.0243 (0.128) | 0.0893 (0.067)# | 0.098 (0.058)# | 0.358 (0.326)#,*,† |
| CD80-CD86- | 0.034 (0.018) | 0.094 (0.073) | 0.166 (0.114)# | 0.384 (0.358)#,* |
| MHChiLy6Clo | ||||
| CD80+ | 0.111 (0.039) | 0.183 (0.114) | 1.172 (0.769)#,^ | 1.075 (0.853)#,† |
| CD86+ | 0.114 (0.040) | 0.207 (0.119) | 1.274 (0.844)#,^ | 1.240 (0.932)#,† |
| CD80+CD86+ | 0.091 (0.033) | 0.170 (0.113) | 1.090 (0.722)#,^ | 1.012 (0.816)#,† |
| CD80-CD86- | 0.110 (0.032) | 0.0789 (0.022) | 0.208 (0.088)^ | 0.330 (0.208)#,*,† |
N=10 mice/group. Mean (SD).
Statistical significance (p<0.05) denoted as #vs. sham; *CIA+LPS vs. CIA, †CIA+LPS vs. LPS, ^CIA vs. LPS.