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. 2025 Apr 9;15:1553969. doi: 10.3389/fonc.2025.1553969

Table 1.

Clinical features of CD20+ PTCL-NOS.

Case Age Sex Clinical presentation B symptoms ECOG Stage IPI score BM involvement LDH Treatments and response Follow-up
1 69 Male Abdominal distension, splenomegaly Present 1 IV 2 Present (Bone marrow biopsy) 215U/L CHOPE×2(PR), Unclear Alive, PFS:23m, OS:23m
2 48 Male Splenomegaly Absent 0 IV 1 Present (Bone marrow biopsy) 184U/L CHOP×1,CHOPE×3(SD),BV+CHPE×2(SD),Azacitidine+Chidamide,Azacitidine+Chidamide+BTZ+CTX(SD),BR(SD) Alive,
PFS:14m, OS:14m
3 61 Female Chest distress, cough, mediastinal mass Absent 1 IV 1 Present (PET/CT) 240U/L CHOPE×4(SD),GemoxD×2, Radiotherapy (PR),R-Gemox-D×4(PR),Azacitidine+Chidamide(PD) Alive,
PFS:14m, OS: 16m

ECOG, Eastern Cooperative Oncology Group performance; IPI, International Prognostic Index; BM, bone marrow; LDH, lactic dehydrogenase; C, cyclophosphamide; H, doxorubicin; O, vincristine; P, prednisone E, etoposide; BV, brentuximab vedotin; BTZ, bortezomib; BR, bendamustine, rituximab; GemoxD, gemcitabine, oxaliplatin, dexamethasone; R, rituximab; PR, partial remission; SD, stable disease; PD, progressive disease; m, months.