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. 2025 Apr 23;40(1):209. doi: 10.1007/s10103-025-04453-4

Table 7.

The improvement on VISIA parameters after 3 treatment sessions

Value Spots Wrinkles Texture Porphyrin UV spots Brown spots Red areas Pores
Age
≤ 45

29.95±

22.46

22.09±

17.31

22.68± 33.01

19.18±

26.41

18 ± 28.22

30.86±

27.37

10.91± 22.72 5.82 ± 18.91
> 45

19.23±

18.50

23.41±

21.99

19 ± 21.03

19.59±

22.37

12 ± 24.97 26.36 ± 20.03 1.95 ± 17.68 11.68 ± 25.77
P value 0.11 0.90 0.87 0.61 0.42 0.78 0.30 0.69
Intense of sun exposure
None 16 14 20 43 2 63 -2 2
15–30 min 25.91± 20.24 27.59± 16.32

26.14±

28.64

16.95± 26.22 17.45± 31.78 31.59± 24.61

5.45±

24.42

8.5 ± 19.97
30–60 min 29 ± 25.07 14.1± 24.64 14 ± 32.40 20.1 ± 21.18 27.8 ± 19.10 25.3 ± 25.96 11.2± 12.79 10 ± 26.68
> 60 min 18.73 ± 20.26

21.73±

20.15

16.55 ± 20.86

21.45±

24.39

0 ± 10.93

22.55±

19.24

4.82±

19.85

8.73 ± 26.43
P value 0.83 0.06 0.63 0.57 0.01 0.49 0.45 0.98
Mask wearing behavior
No 7 ± 9.75 24.2± 20.05 4.2± 10.47 17 ± 10.98 6 ± 25.96 26.6 ± 7.09 1.4 ± 2.88 -11.8± 17.08
Often 29.42± 20.62 24.85 ± 21.96 20.81 ± 30.94 20.88 ± 26.83 15.73± 24.39 31.54± 22.05

7.38±

17.80

11.08±

21.87

Always 21.69± 21.94 18± 14.11

27.31±

22.39

17.31±

23.35

17 ± 31.86

23.54±

30.88

6.46±

29.13

12±

22.95

P value 0.03 0.87 0.14 0.84 0.48 0.40 0.76 0.07
Frequency of sunscreen use
No 13.75± 14.93 28.25± 16.26 14.25± 20.73 14.5 ± 9.18 14 ± 23.47 34.25± 10.72 3.25± 6.65 1.75± 5.32
Often 26.67± 22.85 21.67± 21.02 24.09± 29.64 20.30± 26.00 15.36± 28.62 29.30± 24.79 8.21± 23.19 9.79 ± 22.40
Always 21± 12.70

24.71±

14.96

9.29± 15.53

17.86±

22.86

13.86±

19.76

22.14 ± 

25.60

-0.14 ± 9.06 7.86± 30.16
P value 0.45 0.59 0.43 0.99 0.89 0.58 0.36 0.55
Glogau photoaging classification scale
Mild 30± 38.97 23.67± 22.50 14.33± 56.92

16±

44.24

-0.33±

1.52

40.67±

31.66

37.33±

36.23

-9.67± 11.50
Moderate 26.81± 17.67 20.88± 14.48 25.5± 26.65 14.31± 20.53 18.56± 30.12 29.31± 28.21 2.5± 16.14 9.06 22.68
Advanced 24.84± 23.62 23.21± 23.77 21.95± 25.93 23.05± 25.92 10.53± 20.85 25.53± 20.38 7.37± 20.91 9.79 ± 22.48
Severe 15.17± 10.82 25.83± 20.11

8.17±

17.91

23 ± 20.28

27.33±

36.27

30.5± 21.51 -1.5± 8.78 13.83± 26.68
P value 0.66 0.96 0.51 0.47 0.50 0.86 0.14 0.32

Values represent the delta (change) from baseline, calculated using absolute scores, ± SD. P-values < 0.05 indicate significant difference