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. 2025 Apr 8;27:e69864. doi: 10.2196/69864

Table 1.

Baseline characteristics of patients in the internal, Duke, and SEERa datasets.

Characteristics Internal dataset (N=306) Duke dataset (N=94) SEER dataset (N=2760)
Age (years), n (%)

>60 42 (13.7) 14 (14.9) 732 (26.5)

≤40 60 (19.6) 21 (22.3) 548 (19.9)

40-60 204 (66.7) 59 (62.8) 1480 (53.6)
Histological type, n (%)

Invasive ductal carcinoma 290 (94.8) 89 (94.7) 2506 (90.8)

Other 16 (5.2) 5 (5.3) 254 (9.2)
ERb, n (%)

Negative 124 (40.5) 40 (42.6) 686 (24.9)

Positive 182 (59.5) 54 (57.4) 2074 (75.1)
PRc, n (%)

Negative 179 (58.5) 52 (55.3) 1093 (39.6)

Positive 127 (41.5) 42 (44.7) 1667 (60.4)
HER2d, n (%)

Negative 212 (69.3) 68 (72.3) 1825 (66.1)

Positive 94 (30.7) 26 (27.7) 935 (33.9)
Molecular subtype, n (%)

HRe–/HER2– 73 (23.9) 29 (30.9) 466 (16.9)

HR–/HER2+ 50 (16.3) 11 (11.7) 182 (6.6)

HR+/HER2– 139 (45.4) 39 (41.5) 1359 (49.2)

HR+/HER2+ 44 (14.4) 15 (16.0) 753 (27.3)
Tf, n (%)

1 36 (11.8) 16 (17.0) 449 (16.3)

2 185 (60.5) 58 (61.7) 1458 (52.8)

3 51 (16.7) 17 (18.1) 578 (20.9)

4 34 (11.1) 3 (3.2) 275 (10.0)
Nf, n (%)

0 43 (14.1) 41 (43.6) 929 (33.7)

1 142 (46.4) 40 (42.6) 1232 (44.6)

2 61 (19.9) 7 (7.4) 343 (12.4)

3 60 (19.6) 6 (6.4) 256 (9.3)
Mf, n (%)

0 295 (96.4) 93 (98.9) 2677 (97.0)

1 11 (3.6) 1 (1.1) 83 (3.0)
S tatus , n (%)

0 252 (82.4) 83 (88.3) 2364 (85.7)

1 54 (17.6) 11 (11.7) 396 (14.3)
Survival time, median (IQR) 25.9 (17.2-36.3) 50.2 (29.3-66.2) 35.0 (15.5-64.0)

aSEER: Surveillance, Epidemiology, and End Results.

bER: estrogen receptor.

cPR: progesterone receptor.

dHER2: human epidermal growth factor receptor 2.

eHR: hormone receptor.

fTNM: tumor, node, metastasis.