Table 2.

Cox regression of clinicopathological variables.

Variables		Patients (N=306), n (%)	Univariable hazard ratio (95% CI); P value	Multivariable hazard ratio (95% CI); P value
Age (years)
	>60	42 (13.7)
	≤40	60 (19.6)	0.36 (0.15-0.87); P=.02	0.45 (0.18-1.12); P=.09
	40-60	204 (66.7)	0.40 (0.20-0.77); P=.01	0.48 (0.24-0.97); P=.04
Histology
	Invasive ductal carcinoma	290 (94.8)
	Other	16 (5.2)	0.31 (0.04-2.22); P=.24	0.30 (0.04-2.25); P=.24
ERa
	Negative	124 (40.5)
	Positive	182 (59.5)	0.74 (0.44-1.27); P=.28	1.05 (0.53-2.09); P=.88
PRb
	Negative	179 (58.5)
	Positive	127 (41.5)	0.54 (0.30-0.98); P=.04	0.45 (0.21-0.96); P=.04
HER2c
	Negative	212 (69.3)
	Positive	94 (30.7)	0.54 (0.29-1.02); P=.06	0.45 (0.23-0.87); P=.02
T d
	1	36 (11.8)
	2	185 (60.5)	1.42 (0.55-3.63); P=.47	1.47 (0.57-3.82); P=.42
	3	51 (16.7)	1.35 (0.44-4.14); P=.60	1.26 (0.40-3.93); P=.69
	4	34 (11.1)	1.73 (0.56-5.29); P=.34	1.58 (0.49-5.08); P=.45
Nd
	0	43 (14.1)
	1	142 (46.4)	1.84 (0.63-5.38); P=.26	1.65 (0.55-4.93); P=.37
	2	61 (19.9)	2.75 (0.89-8.55); P=.08	2.06 (0.65-6.58); P=.22
	3	60 (19.6)	4.34 (1.45-12.96); P=.01	3.36 (1.10-10.24); P=.03
Md
	0	295 (96.4)
	1	11 (3.6)	3.30 (1.31-8.31); P=.01	2.74 (1.03-7.25); P=.04

^aER: estrogen receptor.

^bPR: progesterone receptor.

^cHER2: human epidermal growth factor receptor 2.

^dTNM: tumor, node, metastasis.