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. 2025 Apr 22;15:13853. doi: 10.1038/s41598-025-97050-y

Table 1.

Comparison of the performance of SARS-CoV-2 antibody assays and positivity rate across various scenarios.

Variable Category Total Positivity rate (%) P value
Rapid IgG LFA test Rapid IgG + IgM) LFA Elecsys CLIA In-house ELISA
Seroprevalence 47.1% 52.4% 46.3% 42.7%
Age 10_14 356 41 46.6 38.2 39.9 0.409
15–18 647 48.5 54.2 49.6 42.9
 > 18 138 56.5 58.7 52.2 49.3
Sex Female 647 46.5 52.5 45.4 45.3 0.045*
Male 494 47.9 52.2 47.6 39.4
Comorbidity No 1116 47.2 52.6 46.7 43.1 0.154
Yes 18 33.2 33.3 27.8 22.2
Do not know 7 71.4 71.4 42.9 28.6
Having contact with a confirmed case No 1129 47 52.3 46.2 42.6 0.608
Yes 12 58.3 58.3 58.3 50
Rapid IgG LFA test 0.000*
Rapid (IgG + IgM) LFA test 0.000*
Elecsys CLIA 0.000*
Overall prevalence( 95% , CI) 42.7%(39.8–45.6)

*Statically significant.