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. Author manuscript; available in PMC: 2005 Sep 13.
Published in final edited form as: Immunol Invest. 2004 May;33(2):213–233. doi: 10.1081/imm-120034231

Figure 6E. Upstream signaling intermediates of p38 MAPK increase GFP expression in MCT-GFP-IL-6 3′UTR cells.

Figure 6E

Cells were transduced with viral particles containing constitutively active MKK-6, MKK-3, or empty vector viral particles in the presence of polybream for 48 hours. GFP expression was measured by FACscan (10,000 cells were sorted in each group). Data indicates that both MKK-6 and MKK-3 can increase GFP expression in MCT-GFP-IL-6 3′UTR cells. These data suggest that both immediate upstream signaling intermediates of p38 MAPK are able to increase IL-6 mRNA reporter activity.