Fig. 4.
KIR2DS1 triggers NK cytolytic activity. Cr51 release assays of CD158a/h-expressing NK clones against P815, C1R, and 221/Cw6 targets. For each clone, percentage specific lysis is shown for isotype-matched control CD56 (black bars) and test CD158a/h (white bars) antibodies. Antibody was added at 0.5 μg·ml-1 for redirected killing assays against P815 or 10 μg·ml-1 for blocking assays against C1R and 221/Cw6. P815 assays were performed in duplicate with <5% deviation in values. Error bars show standard deviations of triplicates.