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. 2025 Apr 23;25:1498. doi: 10.1186/s12889-025-22544-3

Table 2.

Characteristics of participants stratified by chronic disease status. NHANES 1999–2018

Variable Overall Chronic diseases p-value
No Yes
Age 70.09 ± 0.10 67.20 ± 0.17 70.67 ± 0.10 < 0.0001
PIR 2.97 ± 0.04 3.31 ± 0.06 2.90 ± 0.03 < 0.0001
BMI 28.95 ± 0.08 27.11 ± 0.14 29.33 ± 0.09 < 0.0001
Height 165.94 ± 0.12 166.57 ± 0.25 165.81 ± 0.13 0.004
Weight 80.00 ± 0.24 75.50 ± 0.49 80.93 ± 0.26 < 0.0001
Waist Circumference 102.03 ± 0.20 96.80 ± 0.42 103.13 ± 0.21 < 0.0001
WBC 7.12 ± 0.03 6.60 ± 0.06 7.23 ± 0.03 < 0.0001
Neutrophil% 59.47 ± 0.10 58.18 ± 0.24 59.74 ± 0.11 < 0.0001
Neutrophils 4.26 ± 0.02 3.89 ± 0.05 4.33 ± 0.02 < 0.0001
CRP 0.49 ± 0.01 0.42 ± 0.03 0.51 ± 0.01 0.005
DII 1.48 ± 0.03 1.21 ± 0.06 1.54 ± 0.03 < 0.0001
Sex 0.29
Female 8311(50.33) 1229(56.49) 7082(54.92)
Male 8201(49.67) 1232(43.51) 6969(45.08)
Ethnicity < 0.0001
Mexican American 2440(14.78) 426(3.72) 2014(3.79)
Non-Hispanic Black 3259(19.74) 348(5.23) 2911(9.17)
Non-Hispanic White 8617(52.19) 1284(82.80) 7333(78.79)
Other Hispanic 1243(7.53) 230(3.75) 1013(3.49)
Other Race - Including Multi-Racial 953(5.77) 173(4.51) 780(4.76)
Citizenship 0.22
Citizen by birth or naturalization 15,340(93.01) 2224(96.68) 13,116(97.10)
Not a citizen of the US 1153(6.99) 234(3.32) 919(2.90)
Marital status < 0.0001
Divorced or separated 2405(14.7) 379(14.41) 2026(12.42)
Married or living with partner 9513(58.15) 1560(69.60) 7953(61.89)
Single 756(4.62) 128(3.64) 628(3.55)
Widowed 3686(22.53) 372(12.35) 3314(22.14)
Annual family income < 0.0001
<$65,000 12,691(80.79) 1767(65.31) 10,924(74.04)
>=$65,000 3017(19.21) 564(34.69) 2453(25.96)
Education < 0.0001
College and above 6969(42.31) 1179(60.11) 5790(50.33)
Middle and high school 6397(38.83) 862(33.33) 5535(39.36)
Primary school and less 3107(18.86) 415(6.56) 2692(10.31)
Smoking status < 0.0001
Never 7928(48.07) 1254(53.93) 6674(47.34)
Ever 6493(39.37) 845(33.68) 5648(41.52)
Current 2070(12.55) 356(12.39) 1714(11.14)
Drinking status < 0.0001
Never 2767(18.15) 400(15.05) 2367(16.11)
Ever 4205(27.58) 464(15.86) 3741(25.06)
Current 8276(54.28) 1444(69.09) 6832(58.82)
DII quartile < 0.0001
Q1 4128(25) 686(32.53) 3442(26.58)
Q2 4130(25.01) 657(25.74) 3473(25.67)
Q3 4126(24.99) 601(23.92) 3525(24.34)
Q4 4128(25) 517(17.82) 3611(23.41)

Continuous variables presented as mean ± SD; categorical variables presented as count (%); PIR, poverty income ratio; BMI, body mass index; WBC, white blood cells; CRP, C-reactive protein; DII, dietary inflammatory index; AHI, annual household income;