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. 2025 Apr 23;25:306. doi: 10.1186/s12872-025-04763-z

Table 3.

Univariate and multiple regression analysis for the change of LVMI

Variables Univariate analysis Multiple analysis
β (95% CI) p value β (95% CI) p value
Age 0.05 (− 0.62 to 1.96) 0.443
Male −2.98 (− 4.53 to 5.70) 0.607
Coronary artery disease –3.54 (–8.22 to 3.98) 0.896
Hypertension 0.28 (-0.96 to 1.84) 0.279
Baseline LV GLS −1.80 (− 3.62 to 2.79) 0.313
Baseline LVMI −2.68 (− 4.53 to − 1.89) < 0.001 −1.73 (− 3.53 to − 0.998) < 0.001
POAF 2.73 (1.13 to 3.38) < 0.001 1.46 (1.29 to 2.75) < 0.001
Postprocedural perivalvular leakage –1.16 (–6.81 to 1.13) 0.259
ACE inhibitor/ARB –1.07 (–3.16 to 1.35) 0.458

ACE, angiotensin-converting enzyme; ARB, angiotensin II receptor blocker; CI, confidence interval; HR, hazard ratio; LV, left ventricular; LVEF, left ventricular ejection fraction; LVMI, left ventricular mass index; POAF, postoperative atrial fibrillation. Postprocedural perivalvular leakage refers to the abnormal gap between the artificial heart valve ring and the patient’s own ring tissue after heart valve replacement, causing blood leakage through the gap