Table 2.
Superior fitness of international MDR clone strains vis-a-vis minor clone isolates demonstrated by propagation assays.
| Article | MDR pathogen | Result of fitness test |
|---|---|---|
| Horvath et al. (2012) | MRSA | ST5, ST22 strains transcend fluoroq. resistant ST30, ST8 minor clone isolates |
| Knight et al. (2012) | MRSA | CC22 strains transcend CC30, ST239 fluoroq. resistant isolates |
| Toth et al. (2014) | MDR K. pneumoniae | ST11, ST15, ST147 strains transcend fluoroq. resistant minor clone isolates |
| Johnson et al. (2015b) | MDR E. coli | ST131 H30 strains transcend minor clone isolates when exposed to fluoroq. |
| Vernon et al. (2019) | MDR C. difficile | GyrA Thre82Ile confers a fitness advantage on 027 strains of C. difficile |